Khapra beetle, Trogoderma granarium is considered as a major threat to stored wheat and other products in all over the world. Their attack is not only limited to wheat grains but also reduces the various products made from it. The losses are defined as a measurable decrease of the food quantity and quality and can be avoided through proper control measures and selection of resistant varieties. During the present study, the different wheat varieties were screened against T. granarium. The initial weight of healthy grains of each variety was recorded properly. The losses caused by pests were categorized on the basis of grain weight loss (%), powder weight (mg) and population of pests emerged. In results, it was observed that the attack of T. granarium was present more or less on all wheat varieties. However, the performance of Marvi and Mehran varieties was found to be resistant against T. granarium and thus recommended for future plantations. The present study will be useful to provide the information for controlling T. granarium on wheat.