Two new species, Globicornis (Globicornis) busei Holloway and Herrmann and Globicornis (Globicornis< i>) lienemanni Holloway and Herrmann (Coleoptera: Dermestidae: Megatominae) from eastern Mediterranean are described and compared with G. picta (Kuster, 1851), the most likely confounding species because of geographical overlap and external similarity. Images of the habitus, ventrites, antenna, aedeagus, and sternite IX are presented. Ten Globicornis (Globicornis) Latreille, 1829 species are now known from the eastern Mediterranean.